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However, recently, it is used in patients who refuse to remove their uterus (Rozenberg et al., 2017)

CREB and the CRTC co-activators: sensors for hormonal and metabolic signals

10.3389/fimmu.2021.682853 43 FontaineE

Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is considered as effective as intramuscular administration for correcting anemia and neurologic symptoms Despite many studies suggesting oral administration of vitamin B 12 to be easy, effective and less costly than intramuscular administration, debate surrounds the effectiveness of the oral route