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NRF2 activates the transcription of SLC7A11 gene partially through recruiting HATs (CBP and p300) (47, 56)

VCE catalyses the capping reaction where standard eukaryotic m7GpppG structure is added to mRNA

It is a potent opioid: as a high-affinity mu-opioid agonist it carries the full opioid risk profile respiratory depression, sedation, tolerance and dependence and its potency means those risks are not trivial [5]