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DNA vaccines encoding HSP90 reduce lupus manifestations and prolong survival in lupus-prone mice by inducing tolerogenic dendritic cells and expanding regulatory T cells (Tregs), thereby suppressing autoimmune responses

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A literature search was conducted using PubMed and Cochrane Library during 20012020

IUFGT is designed to deliver genetic material to specific cells in a developing fetus, leveraging various aspects of fetal development to enhance the efficiency, safety, and longevity of therapeutic delivery [164]

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