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With the right approach, peptides can stimulate different biological functions which assist in things like immune system regulation, tissue repair, and neuroprotection

Novel therapeutic strategies targeting gut microbial metabolic pathways and/or metabolites, as well as altering gut microbial composition, have the potential to modulate cardiovascular disease susceptibility and prevent progression to HF

doi: 10.3389/fnmol.2023.1113081 Received 01 December 2022 Accepted 06 March 2023 Published 23 March 2023 Volume 16 - 2023 Edited by Sara Anna Bonini, University of Brescia, Italy Reviewed by Franca Codazzi, San Raffaele Hospital (IRCCS), Italy

Ferroptosis, a recently identified ferroptosis-dependent pathological process characterized by peroxidation and the inactivation of GSH and GPX4, has been shown to be induced by the CCH-mediated inactivation of System Xc-associated transporter proteins ( Our metabolomic analysis showed that, when compared to 2VO group expression, most of the DEMs in RY-A were enriched in fatty acid biosynthesis (ko00061), biosynthesis of unsaturated fatty acids (ko01040), ferroptosis (ko04216), and glutathione metabolism (ko00480)

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