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Most people feel a brief pinch, then a sensation of pressure or heaviness rather than ongoing sharp pain

Heterozygous germline mutations in BMPR2 , encoding a TGF- receptor, cause familial primary pulmonary hypertension

Ecotoxicol Environ Saf 290:117736

0.2% cuprizone (ChemSupply) was delivered for 3 weeks either mixed into control powdered feed (Specialty Feeds, Perth, Western Australia) or as cuprizone-containing pellets (Specialty Feeds, Perth, Western Australia)