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In fact, besides an overall identity of 79% that is somewhat lower than the average identity for other membrane transporters between human and mouse/rat isoforms, in ASCT2 there is a stretch of about 30 amino acids that is profoundly divergent in the different species (Pochini et al., 2014)

Sibarov DA, Vol'nova AB, Frolov DS, Nozdrachev AD

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Upregulation of TLR4 was observed in the renal tubules of DKD biopsies and positively correlated with interstitial macrophage infiltration

[DOI] [PMC free article] [PubMed] [Google Scholar] 306.Kawamura T., Radak Z., Tabata H., Akiyama H., Nakamura N., Kawakami R., Ito T., Usui C., Jokai M., Torma F., et al