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Maintaining optimal levels of glutathione appears to be important for supporting cognitive function, especially as we age.* The normal process of aging is associated with a decrease in glutathione regulation, which can result in increased oxidative activity.* Less than optimum levels of glutathione are observed in individuals experiencing a decline in cognitive function.* Conversely, individuals living over 100 years tend to have higher glutathione reductase activity.* A common mistaken belief is that glutathione is not well absorbed when its taken orally, but significant data confirms it is efficiently absorbed across the intestinal epithelium by a specific uptake system.* Glutathione-SR from Thorne Research represents an important breakthrough in glutathione supplementation

PMID: 32322486

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adult neurogenesis hippocampal neurogenesis hippocampus inducible Cre recombinase neurogenesis tamoxifen Significance Statement Numerous transgenic mouse models use the inducible Cre-Lox system in which a synthetic estrogen tamoxifen (TAM) is used to initiate recombination of genetic sequences flanked by LoxP sites

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