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April 18 Product: Genentechs Alecensa Indication: Non-small cell lung cancer The FDA approved Genentechs Alecensa Thursday as the first adjuvant treatment for patients with early-stage, anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer who have undergone tumor resection

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SS-31, also known as Elamipretide, Bendavia, or MTP-131, is a synthetic tetrapeptide with the sequence D-Arg-dimethyltyrosine-Lys-Phe-NH2

In contrast, CD63-mediated packaging resulted in a higher Cas12f loading per EV than MIM I-BAR through rapamycin-induced dimerization, with an average Cas12f molecules per l-EV of 7.7 0.65 and 55.3 1.3 without and with 100 nM rapamycin treatment, respectively (Fig