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Intratumor heterogeneity and cell secretome promote chemotherapy resistance and progression of colorectal cancer

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Representative CMs and their related mechanisms are summarized in Table 1

The abdomen offers the largest surface area, making it ideal for establishing a rotation pattern with multiple injection zones

Introduction Liver fibrosis develops during the progression of chronic liver disease (e.g., viral hepatitis, alcoholic and nonalcoholic fatty liver disease) to cirrhosis, hepatic failure, or hepatocellular carcinoma, and is caused by hepatic damage repair decompensation