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Emerging roles of proteases in tumour suppression

To examine this, we treated mice with titrated amounts of the AAV-TBG-Cre virus to induce varying degrees of Gclc deletion

Preclinical studies have demonstrated that NCoR1 depletion, followed by treatment with rapamycin, anti-mycin-A, or metformin restored TFEB activity and LC3 levels, leading to improved clearance of M.tb [28]

The uptake of cytoplasmic glutamate into exocytotic vesicles is mediated by vesicular glutamate transporters (VGLUTs), which are driven by a proton gradient produced by vacuolar-type H + ATPases (V-ATPases

I., Karimulla, S., Alasmari, F., Aldalin, H