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During Phase III clinical trials, increased liver enzymes indicated potential hepatotoxicity, with most patients reaching peak ALT levels within four days of starting treatment

Severe deficiency in humans is rare and normally occurs with fat malabsorption disorders

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see also Sneeboer et al., 2019), all of which represent urgent clinical targets for intervention

Available to the public in the form of dietary supplements for the past few decades, this molecule, discovered in 1899, was studied extensively in the 1990s, particularly in the fields of pulmonology, immunology and neurology (2)