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Notably, PPAR alone is not sufficient to restore redox homeostasis and promote the M2 phenotype, as demonstrated by the exacerbation of neuroinflammatory cytokine production in NRF2-deficient mice challenged with LPS (Innamorato et al., 2008)

Plants treated with GSH had higher SOD activity than control plants, but LT plants had lower SOD activity

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*Correspondence: Lin Wu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

SAM-dependent enzymes catalyse the transfer of methyl groups into acceptor molecules via a variety of mechanisms that continue to be investigated extensively [2,3,4,5]