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The main reason is that GSH-Au NCs@His does not have the capacity to form an Au-S bond, which greatly reduces the effectiveness of GSH-Au NCs@His to consume GSH, thus protecting tumor cells from ROS oxidative damage (Figure 7C)

Effects of rituximab therapy on quality of life in patients with primary Sjgrens syndrome

Environ Pollut 292:118390 Hou L-S, Zhang Y-W, Li H, Wang W, Huan M-L, Zhou S-Y et al (2022) The regulatory role and mechanism of autophagy in energy metabolism-related hepatic fibrosis

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Nonetheless, clinical trials have shown that MEK inhibitors can lead to adverse effects, and cancers can develop adaptive resistance mechanisms [44]