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These genomic alterations enable Leishmania to develop resistance through various mechanisms including altered drug transport, target modification, and enhanced metabolic detoxification pathways (Ponte-Sucre et al., 2017)

Steroidal lactones from Withania somnifera , an ancient plant for novel medicine

In summary, although current studies suggest that ferroptosis plays a central regulatory role in the pathological sequence of PVLlinking hypoxiaischemia, inflammatory infiltration, and white-matter necrosisand provides a new mechanistic basis for understanding the pathway from periventricular iron accumulation to oligodendrocyte loss and motor developmental impairment, several essential gaps remain

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CrossRef An analysis of the burden of liver cirrhosis: Differences between the global, China, the United States and India Keqiang Lu, Juanjuan Sui, Wenhui Yu, Yan Chen, Zhiyong Hou, Pengyan Li, Yuli Sun Liver International .2024