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Boudina S, Sena S, ONeill BT, Tathireddy P, Young ME, Abel ED

(2002) Thioredoxins are required for protection against a reductive stress in the yeast Saccharomyces cerevisiae

Thats because glutathione is a triple threat to toxins: It neutralizes free radicals, enhances the immune system, and detoxifies the liver

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In cancer cells, the use of glutamate-derived nitrogen for NEAA production may be favored in various types of cancer cells to preserve nitrogen for anabolic reactions 48 and may prevent apoptosis induced by ATF4 activation upon glutamine deprivation 6