melanotic macule lips macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Simple cryosurgical treatment of the

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Indentations or depressions in the scalp can occur following injections but are much less common when low concentrations are used than when high concentrations are used

In silica-induced fibrosis models, blocking glycolysis or HIF-1 signaling reduces intracellular glycine levels, which correlates with decreased collagen deposition and attenuated fibrotic responses [110]

That shift in timescale is not just a pharmacological footnote