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GSH is involved in the detoxification of free radicals, peroxides and xenobiotics (drugs, pollutants, carcinogens, etc.), protects biological membranes from lipid peroxidation, and is an important regulator of cell homeostasis, since it participates in signaling redox, regulation of the synthesis and degradation of proteins (S-glutathionylation), signal transduction, various apoptotic processes, gene expression, cell proliferation, DNA and RNA synthesis, etc

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Amantadine effect on perceptions of irritability after traumatic brain injury: results of the amantadine irritability multisite study

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This is in agreement with earlier studies describing that Simkania containing vacuoles (SnCV) are in close contact to the ER and recruit and affect mitochondria of infected host cells 47,78