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GHK-Cu: Repair Through Copper Signaling Mechanism of Action: GHK-Cu is a copper-binding peptide that enhances tissue remodeling, reduces oxidative stress, and promotes stem cell activation

Am J Cardiol 2016;117:1427-32

As used herein, the term isotype constant region or Fc region is used interchangeably to define the C-terminal region of an immunoglobulin heavy chain, including native sequence Fc region and variant Fc regions

In addition, more lipophilic drugs will tend to pass not only through the BBB, but also to other organs, which consequently results in a reduced availability of drugs to enter the brain (27)