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However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)

Another important feature of CAF metabolism is increased glutamine synthesis and secretion

If you have symptoms like persistent fatigue or tingling in your hands or feet, a professional assessment is the most important next step

The infusion then runs slowly over one to two hours