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4Pevec D, et al

For instance, alginate CpG hydrogels or chitosan-based depots have demonstrated sustained DC activation and prolonged immune stimulation in preclinical melanoma models, yet such materials also introduce workflow complexity and manufacturing burden

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A review of B vitamins and one-carbon metabolism highlights the importance of vitamin B12 and folate in the methylation cycle to generate methyl groups for use in DNA synthesis, amino acid homeostasis, antioxidant generation, and epigenetic regulation