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Description

Transgenic mice carrying the erythropoietin gene promoter linked to lacZ express the reporter in proximal convoluted tubule cells after hypoxia

Other pathogenic species that target TJ protein complexes to disrupt gut barrier integrity include Vibrio cholerae and Aeromonas hydrophila which secrete a hemagglutinin/protease and a pore-forming aerolysin, respectively, facilitating the direct cleavage of occludin (Nava et al