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Versatility of the Complement System in Neuroinflammation, Neurodegeneration and Brain Homeostasis

Animals were maintained in standard, species-appropriate housing and managed consistently during the study, including providing access to activity/exercise

By modulating PKC activity, rutin effectively suppressed VSMC ferroptosis, thereby contributing to the mitigation of PAH [149]

Critically, both subjects and investigators were blinded to the group assignment, ensuring impartiality throughout the study