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*Correspondence: Faming Jiang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Figure 2 Beyond TLR-dependent mechanisms, gut microbial communities exert significant regulatory control over mucosal 5-HT production (117, 118)

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Week 3-4 What to expect : Significant pain reduction (50-70%) Improved range of motion Better strength Functional improvements Visible progress Week 5-6 What to expect : Near-complete healing (70-90%) Return to activities Minimal discomfort Continued improvement Post-protocol (weeks 7-10) What to expect : Continued healing for 2-4 weeks after stopping Further improvements Stabilization Read complete BPC-157 benefits