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The ovaries rely on a delicate balance of hormonesespecially estrogen, progesterone, LH (luteinizing hormone), and FSH (follicle-stimulating hormone)to regulate ovulation

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Also, misplacement of recombinant gene therapy products has been associated with lower extremity paralysis after intradural injection, and with paraesthesia, systemic illness, and death after epidural injection [94, 95]

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