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The resulting oxidative stress promotes DNA breaks and upregulates PARP-1 expression (27)

PLoS One 7 , e49639 (2012)

In the EAE model, elevated iron levels, lipid peroxidation, and mitochondrial morphological changes were observed in the spinal cord tissue of EAE mice, indicating the presence of classical biochemical alterations and pathological features of ferroptosis

192 A systematic review comparing routine care to brief interventions, gradual dose reduction and psychological interventions found all interventions increased benzodiazepine discontinuation over routine care, with gradual dose reduction plus psychological interventions the most effective

Verify the amount before calculating reconstitution ratios