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When storage capacity is exceeded, excess fatty acids spill into the circulation, accumulate in non-adipose tissues, and promote lipotoxic pathology (98, 99)

doi: 10.2340/00015555-0180

Importantly, these epigenetic alterations have been shown to persist beyond the period of active androgen exposure, even after partial normalisation of circulating hormone levels

rosea operates through BDNF/TrkB signaling pathways, serotonergic modulation, and neuroprotective mechanisms, underscoring its potential as a safe and efficacious alternative or adjunctive treatment in the management of depression

2a) in agreement with previous measurement of the MT3 transcript in MS 24