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The key difference is concentration

The authors reported a case of a patient with cobalamin deficiency who was recommended by her primary neurologist to commence treatment with ocrelizumab, a potent anti-CD20 B-cell depleting monoclonal antibody, after being diagnosed with primary progressive MS

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It is not appropriate to unbundle when procedures were performed in the same eye and same structure (posterior segment)

Some studies suggest that individuals with low levels of B12 are more prone to developing age-related cognitive decline and that supplementation can slow down or even reverse certain symptoms of mental impairment