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Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication

Preparing to do a skin Endpoint Titration Test is time consuming and labour intensive requiring a trained scientific officer or doctor to perform the tests

Wu H, Zhou M, Xu J, Wang J, Tong J, Sun N, Qian M (2022) Determining a wide range of antibiotics and pesticides in poultry feathers using selective accelerated solvent extraction-liquid chromatography-mass spectrometry

With the increasing F1 peptide concentrations, from 0.8 to 3.2 M, the V max value decreased from 0.833 mol/mg/min to 0.645 mol/mg/min, K i value increased from 4.0 M to 5.82 M, and [I]/K i value increased from 0.2 to 0.55