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Description

Front Microbiol (2011) 2:88

- Previne o catabolismo

doi: 10.1111/j.1365-2796.2009.02079.x 303 JammesYSteinbergJGDelliauxS

The bacterial metabolite indolepropionic acid (IPA), derived from tryptophan metabolism, exerts cytostatic effects on metastatic breast cancer cells, that is, it inhibits cancer cell proliferation and movement, decreases epithelial-to-mesenchymal transition, and enhances ROS production and lymphocyte infiltration into the tumor without harming non-cancerous cells surrounding the tumors (263)