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Evidence was graded as Class II (probably effective) per American Academy of Neurology guidelines [5][25]

Bieri JG

(PubMed) Hu L, Li Y, Liu Z, et al

GSH depletion can be a consequence of the inactivation of SLC7A11 of system Xc- which impairs the importing of cystine and hence the available cysteine needed for GSH synthesis [15]