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However, the high total-body content of glutathione (probably in the range of 40 to 80 gm in a 70 kg adult) and the relatively short half-life of this reactive and metabolically important compound (4 to 10 hours in most tissues) render glutathione replacement extremely difficult to achieve in practice

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Identification of novel antioxidant gene signature to predict the prognosis of patients with gastric cancer

Clinical description All patients with 5-oxoprolinase deficiency have been identified because of 5-oxoprolinuria (4 to 10 g/day

Statements Author contributions AEP conceived the idea, surveyed the literature and wrote the manuscript