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Apart from the caspase-dependent pathway, cytoplasmic Omi/HtrA2 also promotes caspase-independent apoptosis by binding and cleaving inhibitors of apoptotic proteins after cisplatin-induced apoptotic stimulation [36]

Oxidative stress-mediated macromolecular damage and dwindle in antioxidant status in aged rat brain regions: role of L-carnitine and DL-alpha-lipoic acid