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Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations (in Eng)

In diet-induced obesity animal models, NNMT inhibition demonstrated metabolic changes including alterations in adipocyte lipid content without affecting food intake patterns, coupled with significant reductions in white adipose tissue mass in treated mice

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Reports also describe shrinkage of adipocyte size and reductions in fat-pad mass while preserving insulin signaling markers in certain models