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By inhibiting the production of pro-inflammatory cytokines and promoting the expression of anti-inflammatory mediators, statins can help create a more favorable environment within the joint, potentially preserving cartilage and soft tissue integrity (142, 143)

De-ionized water, vegetable glycerin, malic acid, citric acid, natural flavors, potassium sorbate (as preservative) and lemon (citrus limon) oil

Propionyl-L-carnitine might increase the effects of warfarin (Coumadin) and increase the chances of bruising and bleeding

To address the issue of multiple comparisons, we employed one-way ANOVA and comparing the mean of each column with the mean of control column LMNA(WT), or no drug control, therefore, we corrected for multiple comparisons using Dunnetts test

Each domain was assessed for the risk of bias, and judgments of low, some concerns, or high were made based on predefined criteria