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Disruption of ATP availability causes deprived ion transport, leading to elevated intracellular Ca 2+ levels, activation of the Gardos channel, cellular dehydration, and diminished deformability (29, 30)

Gene expression of GR revealed up-regulation, like in most chosen genes encoding antioxidant enzymes, (Fig

Plant Pathol 68:16071615

Prior to the initiation of Depakote ER therapy, evaluation for UCD should be considered in the following patients: 1) those with a history of unexplained encephalopathy or coma, encephalopathy associated with a protein load, pregnancy-related or postpartum encephalopathy, unexplained mental retardation, or history of elevated plasma ammonia or glutamine