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Description

verified by -radiation mouse model that resveratrol suppressed oxidative stress induced by ionizing radiation by activating SIRT-1 and others, alleviating radiation pelvic inflammation 41

10.2174/011573403X314035241006185109 168 PardinaE.TondoM.Escol-GilJ

doi: 10.1038/s41598-020-79478-6 29 da Silva DantasA.LeeK

CAFs and ROS engage in two-way cross-talk: on the one hand, fibroblasts are targeted by ROS, particularly H 2 O 2 , which is able to convert them into active CAFs through the upregulation of HIF1