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Animal studies demonstrate enhanced collagen organization and improved biomechanical strength in healing tendons treated with the peptide

After the treatment with test samples for 48 h, the medium was replaced with fresh medium every three days and cultured for 1014 days

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66 Subsequently, downstream transcription factors including nuclear factor-B (NF-B), activator protein-1 (AP-1), and IFN regulatory factor 3/7 (IRF3/7) are activated to promote the transcription of pro-inflammatory cytokines and IFN-I