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The molecular docking results revealed the ability of both n-hexadecanoic acid and L-carnitine to activate SIRT1 and subsequent antioxidant, anti-inflammatory, and anti-apoptotic pathways

Three covalent inhibitors containing acrylamide Since the activity of covalent inhibitors is key to the success of treatment, neither activity is too strong to result in off-target nor activity too weak to bind

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For mice of susceptible strains, cuprizone feeding results in oligodendrocyte cell loss and demyelination of the corpus callosum

Wang C, Ma C, Fu K, Liu Y, Gong L, Peng C, et al