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10 th ed: John Wiley & Sons, Inc

Prolonged exposure to elevated fatty acid levels triggers lipotoxicity, compromising pancreatic -cell functionality and viability

The non-glycosylated forms, called anthocyanidins, include cyanidin, delphinidin, malvidin, peonidin, and petunidin

When this barrier is compromised by oxidative stress, the skin loses its ability to retain moisture effectively, leading to dryness, flakiness, and premature aging