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Description

The maleimide-DAC linker on CJC-1295 achieves the same result by a similar albumin-binding mechanism, extending half-life from 30 minutes to 68 days as reflected in the peptide half-life chart data above

Response: We thank commenters for raising concerns regarding possible ( conflicts with the requirements for the Information Transfer PRO-PM survey and the OAS CAHPS guidelines

The cells were lysed in 25 mM Tris-HCl (pH 7.5), 200 mM NaCl, 0.1% -mercaptoethanol, 10 mM MgCl 2 , 2.1 mM leupeptin, 1.53 mM aprotinin and 50 U of benzonase (Novagen)