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Methionine is activated by adenosine triphosphate leading to the generation of S-adenosylmethionine (SAM), which is a ubiquitous methyl group donor as it donates methyl groups in transmethylation reactions involved in the synthesis or activation of a wide range of bioactive compounds such as DNA, proteins, neurotransmitters, and membrane phospholipids, all of which are regulators of important physiological processes (Reference Bailey, Stover and McNulty5)

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At the study endpoint, tumors were harvested for analysis of incidence, weight, and gross morphology

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