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Peer-reviewed and received in revised form 11 January 2022

The New England Journal of Medicines publication of the STEP trial revealed more than 50% of trial participants lost 15% of their body weight, and between 33-40% of participants lost 20% of their body weight

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So, B12 injections can last for one month with slow release into the blood. In contrast, an IV (intravenous) infusion gives you the dose immediately so that you get the benefits immediately, and the effects are shorter lived