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They should be sourced from licensed compounding pharmacies, not unregulated online vendors, and used with appropriate lab monitoring

Make serial dilutions in compatible buffers and document exact dilutions and solvent compositions

Blood, 112(6), pp.2214-2221

Thus, while the estimation of the amount of a loading dose may be quite correct, the rate of administration can sometimes be crucial in preventing excessive drug concentrations, and slow administration of an intravenous drug (over minutes rather than seconds) is almost always prudent practice

While anecdotal evidence and ongoing research can provide some guidance, consulting with healthcare professionals or fitness experts is paramount