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Figure 11 The phosphinic group is, as compared to, e.g., thiols and hydroxamic acids more weakly binding to zinc ions in metalloproteases and a significantly improved selectivity could be achieved by systematic variations of the side chains at P1 and P2 positions of 43

10.1371/journal.pone.0220397 18

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Harmful molecules are called reactive oxygen species (ROS) and the damage they cause is called oxidative stress

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