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Description

These authors found that toxic IAPP oligomers initially appear within the granules in the secretory pathway, where they disrupt the membranes of the granules, leading to their release into the cytoplasm

Epub 2009 Jan

Wolfson, C., Gauvin, D

252,253 Mitophagy removes dysfunctional mitochondria, thereby preventing the release of mitochondrial components into the cytosol or extracellular space and reducing inflammation