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Oxaliplatin-Induced Gamma-H2ax Activation Via Both P53-Dependent and -Independent Pathways But Is Not Associated With Cell Cycle Arrest in Human Colorectal Cancer Cells

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A reliance on animal experiments may be misleading, given the substantial changes, not only in UA metabolism but also in its transport, associated with primate evolution 62

Inositol causes a significant enhancement in glutathione activity, facilitating glutathiones antioxidant capabilities

Also, proteins and peptides can be metabolized in the cecum and colon [189], as protein fermentation lead to branched SCFAs production [188]