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Such events can cause cartilage to disappear, leading to long-term problems if not treated right

Microtubule assembly dynamics: an attractive target for anticancer drugs

Based on the relevance of p53 in check-point signaling, such findings indicate that PER2 association with p53 might be a regulatory module that influences p53s downstream response to genotoxic stress

All GSLs feature an O -sulfated ( Z )-thiohydroximate core connected to a -D-glucopyranose unit and an amino acid-derived side-chain, with their structural diversity stemming from their variable side-chain origin and modification during biosynthesis

Variants in the intronic or flanking regions of the genes directly involved in the thiopurine pathway were correlated with unfavorable treatment response, but the functional impact of the variants was unclear (Matimba et al., 2014)