why does acetyl l carnitine give me migraines Frontiers Carnitine Responsive Migraine Headache Syndrome:

The late response is regulated by activated T cells expressing and secreting chemokines, monocyte chemotactic proteins, IL-8, eosinophil chemokines, and macrophage inflammatory proteins 4-6 hours after the reaction is initiated

10.1038/ng0793-227

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This is due to the fact that H 2 O 2 can quickly and readily diffuse through cell membranes, primarily through aquaporins (AQPs) 29,30 , as well as between neighbouring cells through gap junctions hemichannels composed of connexins which facilitate the transfer of molecules 13 kDa large such as ROS between cells to propagate oxidative signals 31

Following the 4-hour fast, blood was collected in green-top tubes via retroorbital bleeding