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In contrast, contemporary NRTIs, such as Tenofovir Alafenamide (TAF), Abacavir (ABC), Lamivudine (3TC), have a much lower affinity for Pol-, significantly improving mitochondrial safety profile

However, the scope of both changes, although statistically significant, was within the limits of accepted norms for healthy people

10.1038/nrc1912 Nat

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2.2 Use of Inhaled Glutathione for Treatment Lung infections, including cystic fibrosis, idiopathic pulmonary fibrosis, and lung disease in individuals with HIV