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Kudoh Y, Aoyama S, Torii T, Chen Q, Nagahara D, Sakata H, et al

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While this may be true for the terminal phase of WD in which massive copper overload causes liver failure, an increasing body of evidence demonstrates that such uncontrolled Fenton chemistry reactions do not drive disease pathogenesis

The identified species-specific metabolites also suggest that caution should be exercised when extrapolating animal experimental data to humans, providing valuable references for future translational research